Chirality Control in Photochemical Reactions: Enantioselective Formation of Complex Photoproducts in Solution
Chirality Control in Photochemical Reactions: Enantioselective Formation of Complex Photoproducts in Solution
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DOI：
10.1071/ch08195
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发表时间：
2008-09
影响因子：
1.1
通讯作者：
C. Müller;T. Bach
中科院分区：
文献类型：
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作者：
C. Müller;T. Bach
近年来，已经开发出新的方法，允许在溶液中光化学形成对映体纯或对映体富集的化合物。本综述中提出的主要策略依赖于在超分子组装体或在定义的 1:1 底物-模板复合物中使用手性络合剂。此外，还讨论了有机催化方法和通过自发结晶获得的固有手性底物的手性转移。合成应用表明，对映选择性光化学领域已经脱离了婴儿期状态，即将成为一个成熟但不断具有挑战性的现代化学领域。
In recent years, new methods have been developed that allow for the photochemical formation of enantiomerically pure or enantiomerically enriched compounds in solution. Major strategies presented in this review rely on the use of chiral complexing agents either in a supermolecular assembly or in a defined 1:1 substrate-template complex. In addition, organocatalytic approaches and a chirality transfer from inherently chiral substrates obtained by spontaneous crystallization are discussed. Synthetic applications show that the area of enantioselective photochemistry has left the state of infancy and is about to become a mature but continuously challenging area of modern chemistry.