THE ALKALOIDS OF KOPSIA-LONGIFLORA MERRILL .1. ISOLATION OF THE ALKALOIDS
THE ALKALOIDS OF KOPSIA-LONGIFLORA MERRILL .1. ISOLATION OF THE ALKALOIDS
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DOI：
10.1071/ch9550129
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发表时间：
1955-01-01
影响因子：
1.1
通讯作者：
MICHAEL, M
中科院分区：
文献类型：
--
作者：
CROW, WD;MICHAEL, M
热带雨林树木长花Kopsia longiflora梅里尔（夹竹桃科）的树皮和叶子含有四种新的生物碱：Kopsinine，C21 H26 O2 N2（0.2%），kopsilongine，C24H30O6N2（0.06%），和科普胺，C25 H30 O 7 N2（0.02%）。树皮中有;和kopsilongine（0.07%），科普胺（0.3%），和kopsiflorine，C23 H28 O 5 N2（0.04%）。在树叶里。树皮还含有β-香树脂（0.35%）。而叶子提供链烷烃的混合物，主要是正三十一烷、β-谷甾醇、甾醇C29 H50 O2和三萜醇乙酸酯C32 H52 O2。 Kopsamine、Kopsilongine和Kopsiflorine各含有两个甲氧基，而Kopsinine仅含有一个; Kopsamine和Kopsilongine也含有亚甲基二氧基。未检测到反应性羰基。生物碱都滴定为一元酸碱，形成单甲碘化物：而在酸性和中性介质中记录的紫外光谱表明，碱性（叔）氮原子不有助于发色系统。
The bark and leaves of the rain-forest tree Kopsia longiflora Merrill (Apocynaceae) contain four new alkaloids ; kopsinine, C21H26O2N2, (0.2 per cent.), kopsilongine, C24H30O6N2 (0.06 per cent.), and kopsamine, C25H30O7N2 (0.02 per cent.) occurring in the bark ; and kopsilongine (0.07 per cent.), kopsamine (0.3 per cent.), and kopsiflorine, C23H28O5N2, (0.04 per cent.) in the leaves. The bark also contains β-amyrin (0.35 per cent.) while the leaves afford a mixture of paraffin hydrocarbons, mainly n-hentri- acontane, β-sitosterol, a sterol, C29H50O2, and a triterpene alcohol acetate, C32H52O2. Kopsamine, kopsilongine, and kopsiflorine each contain two methoxyl groups, while kopsinine contains only one ; kopsamine and kopsilongine also contain methylene-dioxy-groups. No reactive carbonyl groups were detected. The alkaloids all titrated as monoacid bases and formed monomethiodides: while the ultraviolet spectra recorded in acid and neutral media show that the basic (tertiary) nitrogen atom does not contribute to the chromophoric system.