Vagal mediation of the effect of alcohol on heart rate.
Vagal mediation of the effect of alcohol on heart rate.
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迷走神经介导酒精对心率的影响。
DOI：
10.1111/j.1530-0277.1990.tb00498.x
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Porges,SW
中科院分区：
文献类型：
--
作者：
Newlin,DB;Byrne,EA;Porges,SW
酒精（0.5克/公斤体重）在两个会议和安慰剂在第三届正常，健康的社会饮酒者。对照组给予混合器（即，不含酒精）的三个阶段。心率和迷走神经张力指数（V）的反应模式是不同的酒精比混合器或安慰剂。治疗对脉搏传导时间的影响无差异。结果表明，中等剂量的酒精对心脏的急性影响是副交感神经的（即，迷走神经）介导的并且没有显著的直接交感神经成分。
Alcohol (0.5 g/kg bodyweight) was administered in two sessions and placebo in a third session to normal, healthy social drinkers. A control group was administered a mixer (i.e., no alcohol) for each of the three sessions. The heart rate and vagal tone index (V) response patterns were different to alcohol than to the mixer or placebo. The treatments did not differentially influence pulse transit time. The results indicated that the acute effect of a moderate dose of alcohol on the heart is parasympathetically (i.e., vagally) mediated and has no significant direct sympathetic component.