Pneumococcal disease among human immunodeficiency virus-infected persons: Incidence, risk factors, and impact of vaccination
Pneumococcal disease among human immunodeficiency virus-infected persons: Incidence, risk factors, and impact of vaccination
复制标题
DOI：
10.1086/319218
复制
发表时间：
2001-03-01
影响因子：
11.8
通讯作者：
Kaplan, JE
中科院分区：
文献类型：
--
作者：
Dworkin, MS;Ward, JW;Kaplan, JE
为了确定与肺炎球菌疾病（肺炎球菌肺炎或侵袭性疾病）相关的因素以及肺炎球菌疫苗对艾滋病毒感染者的影响，我们分析了成人和青少年艾滋病毒疾病谱项目收集的1990年1月至1998年12月期间的患者数据。在39，086人和71，116人年（py）的观察中，诊断出585例肺炎球菌病（发病率为8.2例/1000 py）。与肺炎球菌疾病风险增加相关的因素（P
To determine the factors associated with pneumococcal disease (pneumococcal pneumonia or invasive disease) and the impact of pneumococcal vaccine in HIV-infected persons, we analyzed patient data collected by the Adult and Adolescent Spectrum of HIV Disease Project for person-time between January 1990 and December 1998. Among 39,086 persons with 71,116 person-years (py) of observation, 585 episodes of pneumococcal disease were diagnosed (incidence, 8.2 episodes per 1000 py). Factors associated with an increased risk for pneumococcal disease (P