Histopathologic features of eosinophilic esophagitis.

Histopathologic features of eosinophilic esophagitis.
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DOI:
10.1016/j.giec.2007.09.014
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发表时间:
2008-01-01
影响因子:
--
通讯作者:
Collins, Margaret H
Collins, Margaret H
中科院分区:
其他
文献类型:
--
作者:
Collins, Margaret H

文献摘要

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嗜酸性食管炎(EE)的病理学在人类中完全发展时具有高度特征性,并且易于与正常食管的组织学区分。组织学改变对于EE的多种病因中的任何一种都不是特异性的,只有当组织学与临床表现相关时才能做出正确的诊断。本文回顾了正常食管的组织学,并与EE的结果进行了对比。简要回顾了与EE相关的人类和动物模型的选定研究。
The pathology of eosinophilic esophagitis (EE) when fully developed in humans is highly characteristic and readily discriminated from the histology of the normal esophagus. The histologic alterations are not pathognomonic for any of the multiple causes of EE, and the correct diagnosis can be made only if the histology is correlated with clinical findings. The histology of the normal esophagus is reviewed and contrasted with the findings in EE. The characteristic findings in EE are illustrated. Selected research in humans and animal models pertinent to EE are briefly reviewed.