Congenital disseminated tufted angioma
Congenital disseminated tufted angioma
复制标题
先天性播散性簇状血管瘤
DOI：
10.1111/cup.12089
复制
发表时间：
2013-04-01
影响因子：
1.7
通讯作者：
Gao, Tianwen
中科院分区：
文献类型：
--
作者：
Wang, Lei;Liu, Ling;Gao, Tianwen
Tufted angioma represents a rare vascular tumor that can develop in children and young adults. It usually presents as solitary plaque or large tumor on the extremities, trunk or other anatomic sites. Histopathologically, it is characterized by proliferation of closely packed capillaries in the dermis in a ‘cannonball’ distribution. We described a 2‐month‐old child who developed widespread disseminated red papules since her birth. Eight lesions were excised for histopathology, seven of which showed typical cannonball‐like distribution of proliferative capillaries, characteristic of tufted angioma, and one on the hand which showed focal disseminated proliferation of endothelial cells. Immunohistochemistry showed focal D2‐40 positivity in one lesion and was negative in the other seven. Expression of Prox1 and Glut‐1 was negative in all lesions. This case represented a disseminated form of tufted angioma.
