Induced electrocorticographic gamma activity during auditory perception
Induced electrocorticographic gamma activity during auditory perception
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DOI：
10.1016/s1388-2457(00)00545-9
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发表时间：
2001-04-01
影响因子：
4.7
通讯作者：
Hao, L
中科院分区：
文献类型：
--
作者：
Crone, NE;Boatman, D;Hao, L
目的：探讨左颞上回功能激活过程中诱发γ (> ~ 30hz)活动的空间、时间和功能特征。方法：对4例临床被试进行听觉声调和音素辨别任务时的脑皮质电图（ECoG）记录，计算脑皮质电图频带功率的事件相关变化。将不同γ波段的事件相关功率变化与听觉诱发电位（AEPs）和α波段（8 ~ 12 Hz）的事件相关功率变化的地形图和时间序列进行对比。结果：听觉刺激诱导了宽带功率增强，包括40赫兹，以及更高（80-100赫兹）的伽马频率。γ增强的形貌与AEP相似，但不完全相同，且比α功率抑制的形貌更集中。它的时间开始与N100一致。但却活了下来。音素比音调产生更大的伽马增强，而在N100中没有观察到类似的差异。结论：听觉不仅能诱发40 Hz的脑电图伽马活动，还能诱发更高频率的脑电图伽马活动。这种活动似乎是皮层激活的一个指标，它比AEP或alpha功率抑制更能反映人类听觉皮层中特定任务的处理。(C) 2001爱思唯尔科学爱尔兰有限公司版权所有。
Objective: To define the spatial, temporal, and functional characteristics of induced gamma (>30 Hz) activity during functional activation of the left superior temporal gyrus.Methods: Electrocorticographic (ECoG) recordings were made in 4 clinical subjects during auditory tone and phoneme discrimination tasks, and event-related changes in the ECoG band power were calculated. The topography and temporal sequence of event-related power changes in different gamma bands were contrasted with those of auditory evoked potentials (AEPs), and with those of event-related power changes in the alpha band (8-12 Hz).Results: Auditory stimuli induced a broadband power augmentation that included 40 Hz, as well as higher (80-100 Hz) gamma frequencies. The topography of gamma augmentation was similar, but not identical, to that of the AEP, and was more focused than that of alpha power suppression. Its temporal onset coincided with the N100. but outlasted it. Phonemes produced greater gamma augmentation than tones, while a similar difference was not observed in the N100.Conclusions: Auditory perception induces ECoG gamma activity not only at 40 Hz, but also in higher gamma frequencies. This activity appears to be an index of cortical activation that reflects task-specific processing in the human auditory cortex more closely than the AEP or alpha power suppression. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.