Anterior cingulate N-acetylaspartate/creatine ratios during clonidine treatment in a maltreated child with posttraumatic stress disorder
Anterior cingulate N-acetylaspartate/creatine ratios during clonidine treatment in a maltreated child with posttraumatic stress disorder
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DOI：
10.1089/10445460152595649
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发表时间：
2001-09-01
影响因子：
1.9
通讯作者：
Harenski, KA
中科院分区：
文献类型：
--
作者：
De Bellis, MD;Keshavan, MS;Harenski, KA
Posttraumatic stress disorder in maltreated children is associated with dysregulation of biological stress systems, adverse brain development, and neuronal loss in the anterior cingulate region of the medial prefrontal cortex. A maltreated boy with posttraumatic stress disorder was followed prospectively using single voxel proton magnetic resonance spectroscopy measures of anterior cingulate N-acetylaspartate/creatine ratios, a marker of neural integrity. N-acetylaspartate/creatine ratios increased, and sleep measures improved upon symptom remission.
