Two tonB systems function in iron transport in Vibrio anguillarum, but only one is essential for virulence

Two tonB systems function in iron transport in Vibrio anguillarum, but only one is essential for virulence
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DOI:
10.1128/iai.72.12.7326-7329.2004
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发表时间:
2004-12-01
影响因子:
3.1
通讯作者:
Crosa, JH
Crosa, JH
中科院分区:
医学2区
文献类型:
--
作者:
Stork, M;Di Lorenzo, M;Crosa, JH

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我们已经确定了两个功能tonB系统的海洋鱼类病原体鳗弧菌,tonB1和tonB2。每个tonB基因在操纵子中与对应的exbB和exbD基因一起转录以响应铁限制。只有tonB2是铁anguibactin和毒力的运输所必需的。
We have identified two functional tonB systems in the marine fish pathogen Vibrio anguillarum, tonB1 and tonB2. Each of the tonB genes is transcribed in an operon with the cognate exbB and exbD genes in response to iron limitation. Only tonB2 is essential for transport of ferric anguibactin and virulence.