IS THE PSEUDO-DYAD IN RETROVIRAL PROTEINASE MONOMERS STRUCTURAL OR EVOLUTIONARY

IS THE PSEUDO-DYAD IN RETROVIRAL PROTEINASE MONOMERS STRUCTURAL OR EVOLUTIONARY
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DOI:
10.1016/0014-5793(90)80103-p
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发表时间:
1990-01-29
期刊:
影响因子:
3.5
通讯作者:
WLODAWER, A
WLODAWER, A
中科院分区:
生物学3区
文献类型:
--
作者:
RAO, JKM;WLODAWER, A

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A pseudo‐dyad was found to exist in the monomers of the crystal structures of the proteinases from Rous sarcoma virus and the human immunodeficiency virus. This dyad, also discovered earlier in pepsin‐like aspartic proteinases and considered to be of probable evolutionary origin, has been shown to arise as a result of the topology and the folding of the proteinase monomers and may not therefore have much evolutionary significance.