Excavating ghost footprints and tangled trees from modern genomes
Excavating ghost footprints and tangled trees from modern genomes
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从现代基因组中挖掘幽灵足迹和纠结的树木
DOI：
10.1111/mec.15141
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发表时间：
2019
影响因子：
4.9
通讯作者：
Therkildsen, Nina Overgaard
中科院分区：
文献类型：
--
作者：
Jacobs, Arne;Therkildsen, Nina Overgaard
由于普遍的基因流动和混合，简单的分叉树往往不能提供一个准确的表示不同的谱系之间的关系，但有限的分辨率在现有的基因组数据和样本的空间分布阻碍了详细的了解许多物种和种群的进化和人口统计学的历史。（2019）联合收割机结合了强大的采样设计与从人类遗传学中采用的新分析方法，以描述全球分布的虎鲸（Orcinus orca）中以前未被识别的谱系之间的经常性分离和混合模式。仅基于现代样本的序列数据，他们就发现了古代混合物与现已灭绝的“幽灵”血统的清晰特征，这是非人类物种中古代基因渗入的第一个解释。将具有成本效益的测序策略与新颖的分析方法相结合，他们的论文为推进其他非模型物种进化历史的推断提供了路线图，为我们的领域带来了令人兴奋的时代。
Due to pervasive gene flow and admixture, simple bifurcating trees often do not provide an accurate representation of relationships among diverging lineages, but limited resolution in the available genomic data and the spatial distribution of samples has hindered detailed insights regarding the evolutionary and demographic history of many species and populations. In this issue ofMolecular Ecology, Foote et al. (2019) combine a powerful sampling design with novel analytical methods adopted from human genetics to describe previously unrecognized patterns of recurrent vicariance and admixture among lineages in the globally distributed killer whale (Orcinus orca). Based on sequence data from modern samples alone, they discover clear signatures of ancient admixture with a now extinct “ghost” lineage, providing one of the first accounts of archaic introgression in a nonhominid species. Coupling a cost‐effective sequencing strategy with novel analytical approaches, their paper provides a roadmap for advancing inference of evolutionary history in other nonmodel species, promising exciting times ahead for our field.
影响因子：
5
作者：
Duranton, Maud;Allal, Francois;Gagnaire, Pierre-Alexandre
通讯作者：
Gagnaire, Pierre-Alexandre
影响因子：
4.5
作者：
Skov L;Hui R;Shchur V;Hobolth A;Scally A;Schierup MH;Durbin R
通讯作者：
Durbin R
影响因子：
4.9
作者：
Buerkle, C. Alex;Gompert, Zachariah
通讯作者：
Gompert, Zachariah