Heart rate variability - a historical perspective.
Heart rate variability - a historical perspective.
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DOI：
10.3389/fphys.2011.00086
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发表时间：
2011
影响因子：
4
通讯作者：
Billman GE
中科院分区：
文献类型：
--
作者：
Billman GE
心率变异性(HRV)，即心率或R-R间期(心脏周期)的节拍变化，已成为一种流行的临床和研究工具。心率的时间波动与呼吸表现出显著的同步性(吸气时增加，呼气时减少--即所谓的呼吸性窦性心律失常，RSA)，被广泛认为反映了心脏自主神经调节的变化。虽然自主神经系统的副交感神经和交感神经分支对这种变异的确切贡献是有争议的，并且仍然是积极研究和辩论的主题，但许多时间和频域技术已经被开发出来，以深入了解心脏自主神经调节在健康和疾病中的作用。本文的目的是对心率变异性概念的演变进行历史回顾。简而言之，脉搏最早是由古希腊的医生和科学家测量的。然而，直到1707年“医生脉搏手表”(一种秒针可以停止的手表)的发明，才能准确地评估脉搏频率的变化。斯蒂芬·黑尔斯牧师(1733)是第一个注意到脉搏随呼吸变化的人，1847年，卡尔·路德维希第一个记录了RSA。随着心电(1895)的测量和20世纪60年代数字信号处理技术的出现，对心率变异性及其与健康和疾病的关系的研究出现了爆炸性的增长。本文最后将对常用的测量心率变异性的时域、频域和非线性动态分析技术(及其局限性)进行简要描述。
Heart rate variability (HRV), the beat-to-beat variation in either heart rate or the duration of the R–R interval – the heart period, has become a popular clinical and investigational tool. The temporal fluctuations in heart rate exhibit a marked synchrony with respiration (increasing during inspiration and decreasing during expiration – the so called respiratory sinus arrhythmia, RSA) and are widely believed to reflect changes in cardiac autonomic regulation. Although the exact contributions of the parasympathetic and the sympathetic divisions of the autonomic nervous system to this variability are controversial and remain the subject of active investigation and debate, a number of time and frequency domain techniques have been developed to provide insight into cardiac autonomic regulation in both health and disease. It is the purpose of this essay to provide an historical overview of the evolution in the concept of HRV. Briefly, pulse rate was first measured by ancient Greek physicians and scientists. However, it was not until the invention of the “Physician’s Pulse Watch” (a watch with a second hand that could be stopped) in 1707 that changes in pulse rate could be accurately assessed. The Rev. Stephen Hales (1733) was the first to note that pulse varied with respiration and in 1847 Carl Ludwig was the first to record RSA. With the measurement of the ECG (1895) and advent of digital signal processing techniques in the 1960s, investigation of HRV and its relationship to health and disease has exploded. This essay will conclude with a brief description of time domain, frequency domain, and non-linear dynamic analysis techniques (and their limitations) that are commonly used to measure HRV.
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影响因子：
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作者：
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通讯作者：
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DOI：
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发表时间：
1989-11-01
影响因子：
24
作者：
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通讯作者：
COHEN, RJ