An evaluation of sex differences in psychological and physiological responses to experimentally-induced pain: a path analytic description
An evaluation of sex differences in psychological and physiological responses to experimentally-induced pain: a path analytic description
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DOI：
10.1016/j.pain.2004.08.017
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发表时间：
2004-11-01
期刊：
影响因子：
7.4
通讯作者：
Ward, LC
中科院分区：
文献类型：
--
作者：
Dixon, KE;Thorn, BE;Ward, LC
采用冷加压作业（CPT）对203名大学生（112名女性和91名男性）进行了疼痛反应性别差异的研究。在疼痛诱导前后进行生理测量，并使用个人属性问卷（PAQ）评估性别差异人格特质。疼痛灾难化量表（PC）在CPT前给予标准说明，并在CPT后重新给予修改后的说明，以评估CPT期间的灾难性思维。假设被制定成一个解释模型，通过路径分析进行评估。疼痛诱导升高血压和皮质醇水平的两种性别，但收缩压反应性和皮质醇反应更大的男性，即使在CPT耐受时间的性别差异控制统计。CPT后PC评分与疼痛评分呈正相关，与耐受性呈负相关，但基线PC评分不能预测耐受性或疼痛评分。前PCS评分与后PCS评分相关性不好（r=0.46），低估了后PCS评分，特别是女性。CPT后PC上的性别差异主要归因于PAQ人格特质的情绪脆弱性。在CPT之前和之后评估灾难化所获得的差异结果强调了指定评估灾难化的背景（时间和指令）的重要性。在构建的灾难化的理论考虑也强调，包括但不限于，混杂的变量，如疼痛强度和不愉快。(C)2004年国际疼痛研究协会。Elsevier B.V.出版，保留所有权利。
A cold pressor task (CPT) was used with 203 college students (112 women and 91 men) in a study of sex differences in pain response. Physiological measures were taken before and after pain induction, and sex-differentiating personality traits were assessed with the Personal Attributes Questionnaire (PAQ). The Pain Catastrophizing Scale (PCs) was given with standard instructions prior to the CPT, and it was readministered after the CPT with modified instructions to assess catastrophic thinking during the CPT. Hypotheses were formulated into an explanatory model that was evaluated by path analysis. Pain induction elevated blood pressures and cortisol levels for both sexes, but systolic blood pressure reactivity and cortisol response were greater in men, even with sex differences in CPT tolerance times controlled statistically. Post-CPT PCs scores were positively related to pain ratings and negatively related to tolerance, but baseline PCs scores did not predict tolerance or pain ratings. Pre-PCS scores were not well correlated with post-PCS scores (r=0.46) and underestimated post-PCS scores, particularly for women. The Sex difference on the post-CPT PCs was largely attributable to the PAQ personality trait of Emotional Vulnerability. The differential results obtained from assessing catastrophizing before and after the CPT emphasized the importance of specifying the context in which catastrophizing is assessed (both timing and instructions). Theoretical considerations in the construct of catastrophizing are also highlighted, including, but not limited to, the confounding of variables such as pain intensity and unpleasantness. (C) 2004 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.