Paradoxical behavior of Plasmodium vivax in the chimpanzee
Paradoxical behavior of Plasmodium vivax in the chimpanzee
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DOI：
10.1016/0035-9203(56)90036-0
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发表时间：
1956-01-01
期刊：
影响因子：
--
通讯作者：
RODHAIN, J.
中科院分区：
文献类型：
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作者：
RODHAIN, J.
在一只雄性黑猩猩（Pan satyrus verus）静脉接种感染间日疟原虫马达加斯加株的斑翅按蚊唾液腺9个月后，在其肝实质切片中发现了红细胞外型嗜酸粒细胞。这种红细胞外期的长时间保留可能表明黑猩猩可能是研究人类疟原虫红细胞外期循环的极好实验动物。这一发现也支持了以下观点：尽管使用了抗疟疾药物，但在所有血型完全消失后，疾病的复发可能是由于疟原虫在肝实质中长时间保留所致。|| 摘要：A. C.沃尔顿
Exo-erythrocytic schizonts were found in slides of the liver parenchyma of a male chimpanzee (Pan satyrus verus) 9 months after it had been inoculated intravenously with salivary glands of Anopheles maculipennis infected with the Madagascar strain of P. vivax. Such a long retention of exo-erythrocytic stages may indicate that the chimpanzee might be an excellent laboratory animal for the study of the exo-erythrocytic cycle of the plasmodia of man. The finding also supports the belief that recurrence of the disease following complete disappearance of all blood forms may be due to the retention of schizonts in liver parenchyma for long periods of time in spite of anti-malarial medication. || ABSTRACT AUTHORS: A. C. Walton