Thermal aging and reduced hydrophobic recovery of polydimethylsiloxane
Thermal aging and reduced hydrophobic recovery of polydimethylsiloxane
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DOI：
10.1016/j.snb.2005.04.037
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发表时间：
2006-03-30
影响因子：
8.4
通讯作者：
Beebe, DJ
中科院分区：
文献类型：
--
作者：
Eddington, DT;Puccinelli, JP;Beebe, DJ
聚二甲基硅氧烷（PDMS）的快速原型制作经常用于构建微流体装置。PDMS本身是疏水性的;然而，通过将表面暴露于氧等离子体，可以暂时使表面亲水。亲水性微通道有时优于疏水性微通道，这是由于在填充水溶液期间增加的细胞粘附到亲水性表面或较少的气泡捕获。然而，亲水性表面是不稳定的，并且低分子量（LMW）链从PDMS的本体扩散并覆盖了亲水性不稳定的表面。然而，通过热老化消除低分子量物质可使亲水性表面更持久。(c)2005 Elsevier B. V.保留所有权利。
Rapid prototyping of polydimethylsiloxane (PDMS) is frequently used to build microfluidic devices. PDMS is inherently hydrophobic; however, the surface can be temporarily rendered hydrophilic by exposing the surface to an oxygen plasma. Hydrophilic microchannels, are sometimes advantageous over hydrophobic microchannels due to increased cell adhesion to hydrophilic surfaces or less air bubble trapping during filling with aqueous solution. However, the hydrophilic surface is unstable and low molecular weight (LMW) chains diffuse from the bulk of the PDMS and cover up the thermodynamically unstable surface. However, eliminating LMW species through thermal aging allows the hydrophilic surface to be more permanent. (c) 2005 Elsevier B.V. All rights reserved.