Prevalence and clinical significance of cardiac murmurs in neonates
Prevalence and clinical significance of cardiac murmurs in neonates
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DOI：
10.1136/fn.80.1.f43
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发表时间：
1999-01-01
影响因子：
4.4
通讯作者：
Wren, C
中科院分区：
文献类型：
--
作者：
Ainsworth, SB;Wyllie, JP;Wren, C
Aim-To determine the prevalence and clinical significance of murs detected during routine neonatal examination. Methods-In a two year prospective study，7204 neonatal babies undertaken routine examination by senior house officers.所有有杂音者均行超声心动图检查。所有的婴儿提出以后在婴儿期也被确定，以确定先天性心脏病在infant.Results-Murmurs的总患病率检测到46名婴儿（0.6%），其中25个有心脏畸形。最常见的诊断是室间隔缺损，尽管有四个婴儿有无症状的左心流出道梗阻。来自同一出生队列的另外32名婴儿有一个正常的新生儿检查，但被发现有心脏畸形前12个月龄。结论新生儿检查检测只有44%的心脏畸形，目前在婴儿期。如果听到杂音，则有54%的可能性存在潜在的心脏畸形。父母和专业人员应该意识到，正常的新生儿检查并不能排除有临床意义的心脏畸形。杂音的检测应促使早期转诊到儿科心脏病专家进行诊断或适当的保证。
Aim-To determine the prevalence and clinical significance of murmurs detected during routine neonatal examination.Methods-In a two year prospective study, 7204 newborn babies underwent routine examination by senior house officers. All those with murmurs underwent echocardiographic examination. All babies presenting later in infancy were also identified, to ascertain the total prevalence of congenital heart disease in infancy.Results-Murmurs were detected in 46 babies (0.6%) of whom 25 had a cardiac malformation. The most common diagnosis was a ventricular septal defect, although four babies had asymptomatic left heart outflow obstruction. A further 32 infants from the same birth cohort had a normal neonatal examination but were found to have a cardiac malformation before 12 months of age.Conclusions The neonatal examination detects only 44% of cardiac malformations which present in infancy. If a murmur is heard there is a 54% chance of there being an underlying cardiac malformation. Parents and professionals should be aware that a normal neonatal examination does not preclude a clinically significant cardiac malformation. The detection of a murmur should prompt early referral to a paediatric cardiologist for diagnosis or appropriate reassurance.