Tcoffee@igs: a web server for computing, evaluating and combining multiple sequence alignments
Tcoffee@igs: a web server for computing, evaluating and combining multiple sequence alignments
复制标题
DOI：
10.1093/nar/gkg522
复制
发表时间：
2003-07-01
影响因子：
14.9
通讯作者：
Notredame, C
中科院分区：
文献类型：
--
作者：
Poirot, O;O'Toole, E;Notredame, C
本文介绍了Tcoffee@igs，一个由惠普计算机公司和国家科学研究中心提供给社区的新服务器。该服务器是一个基于web的工具，专门用于多个序列比对的计算、评估和组合。它使用最新版本的T-Coffee软件包。给定一组未对齐的序列，服务器返回经过评估的多序列对齐和相关的系统发育树。该服务器还可以评估现有校准的本地可靠性，并将几个备选的多个校准组合为一个新校准。Tcoffee@igs可用于对齐蛋白质，RNA或DNA序列。可以处理多达100个序列（2000个残基长）的数据集。该服务器及其文档可从http://igs-server.cnrs-mrs.fr/Tcoffee/获得。
This paper presents Tcoffee@igs, a new server provided to the community by Hewlet Packard computers and the Centre National de la Recherche Scientifique. This server is a web-based tool dedicated to the computation, the evaluation and the combination of multiple sequence alignments. It uses the latest version of the T-Coffee package. Given a set of unaligned sequences, the server returns an evaluated multiple sequence alignment and the associated phylogenetic tree. This server also makes it possible to evaluate the local reliability of an existing alignment and to combine several alternative multiple alignments into a single new one. Tcoffee@igs can be used for aligning protein, RNA or DNA sequences. Datasets of up to 100 sequences (2000 residues long) can be processed. The server and its documentation are available from: http://igs-server.cnrs-mrs.fr/Tcoffee/.