Loss of vascular fibrinolytic activity following irradiation of the liver--an aspect of late radiation damage.
Loss of vascular fibrinolytic activity following irradiation of the liver--an aspect of late radiation damage.
复制标题
肝脏照射后血管纤溶活性丧失——晚期辐射损伤的一个方面。
DOI：
10.2307/3576107
复制
发表时间：
1983
影响因子：
3.4
通讯作者：
R. J. Johnson
中科院分区：
文献类型：
--
作者：
B. Henderson;H. Bicher;R. J. Johnson
通过对接受放射治疗的小猎犬肝脏样本进行纤维蛋白溶解自显影，研究了血管纤维蛋白溶解活性，已知其起源于内皮细胞。献祭前18至30个月，6只狗接受X射线照射（5周内4600 rad）， 3只狗接受X射线照射加阿司匹林（1 g/kg）。两只狗作为未经治疗的对照组。对照肝脏显示与大小血管结构相关的广泛的纤溶活性。除主要的门静脉分支外，5个肝脏的血管纤溶活性均丧失，3个肝脏的纤溶活性严重减弱。一个受辐照的肝脏似乎具有正常的纤溶活性。
The vascular fibrinolytic activity, known to originate from the endothelium, was studied histochemically by fibrinolysis autography in liver samples from beagles exposed to radiation treatment. Eighteen to thirty months prior to sacrifice, six dogs received X irradiation (4600 rad in 5 weeks) and three dogs received X irradiation plus aspirin (1 g/kg). Two dogs served as untreated controls. Control livers showed extensive fibrinolytic activity related to large and small vascular structures. The vascular fibrinolytic activity had been lost from all vessels except the major portal branches in five irradiated livers and was severely diminished in three. One irradiated liver appeared to possess normal fibrinolytic activity.
DOI：
--
发表时间：
1981
期刊：
Cancer clinical trials
影响因子：
--
作者：
Zook,BC;Bradley,EW;Casarett,GW;Hitzelberg,RA;Rogers,CC
通讯作者：
Rogers,CC