Trading off spatio‐temporal properties in 3D high‐speed fMRI using interleaved stack‐of‐spirals trajectories
Trading off spatio‐temporal properties in 3D high‐speed fMRI using interleaved stack‐of‐spirals trajectories
复制标题
使用交错的螺旋轨迹堆栈权衡 3D 高速 fMRI 中的时空特性
DOI：
10.1002/mrm.28742
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发表时间：
2021
影响因子：
3.3
通讯作者：
Hennig J
中科院分区：
文献类型：
--
作者：
Riemenschneider B;Akin B;LeVan P;Hennig J
目的已提出高度欠采样采集来突破功能 MRI 时间分辨率的极限。此贡献旨在识别参数集，让用户通过改变采样密度在超高时间分辨率和空间信号质量之间进行权衡。所提出的方法保持了时间分辨率的协同作用，能够直接过滤生理伪影以获得最高的统计能力，并通过优化使用多线圈阵列的编码功能来实现3D读出，以实现高效采样和高信噪比（SNR）。方法使用不同的采样密度，以3毫米的标称分辨率，重复时间从96到352毫秒的一到四次交错球形螺旋轨迹比较图像质量和时间 SNR (tSNR)。在静息态研究中采用单次和三次轨迹进行功能表征。结果与先前描述的单次轨迹相比，除了点扩散函数的可变密度伪影之外，相同类型的更密集的采样轨迹更不容易出现模糊和失共振漏洞。虽然多镜头轨迹导致 tSNR 效率降低，但 3D 读出带来的高 SNR 加上图像质量的显着提高，导致三镜头交错螺旋堆叠的整体效果优异。对 15 名受试者的静息状态分析显示，高偏共振梯度区域的功能灵敏度显着提高。结论 轻度可变密度采样可带来出色的 tSNR 行为，并且不会增加偏共振脆弱性，除非寻求最大时间分辨率，否则建议采用轻度可变密度采样。
PurposeHighly undersampled acquisitions have been proposed to push the limits of temporal resolution in functional MRI. This contribution is aimed at identifying parameter sets that let the user trade‐off between ultra‐high temporal resolution and spatial signal quality by varying the sampling densities. The proposed method maintains the synergies of a temporal resolution that enables direct filtering of physiological artifacts for highest statistical power, and 3D read‐outs with optimal use of encoding capabilities of multi‐coil arrays for efficient sampling and high signal‐to‐noise ratio (SNR).MethodsOne‐ to four‐shot interleaved spherical stack‐of‐spiral trajectories with repetition times from 96 to 352 ms at a nominal resolution of 3 mm using different sampling densities were compared for image quality and temporal SNR (tSNR). The one‐ and three‐shot trajectories were employed in a resting state study for functional characterization.ResultsCompared to a previously described single‐shot trajectory, denser sampled trajectories of the same type are shown to be less prone to blurring and off‐resonance vulnerability that appear in addition to the variable density artifacts of the point spread function. While the multi‐shot trajectories lead to a decrease in tSNR efficiency, the high SNR due to the 3D read‐out, combined with notable increases in image quality, leads to superior overall results of the three‐shot interleaved stack of spirals. A resting state analysis of 15 subjects shows significantly improved functional sensitivity in areas of high off‐resonance gradients.ConclusionMild variable‐density sampling leads to excellent tSNR behavior and no increased off‐resonance vulnerability, and is suggested unless maximum temporal resolution is sought.
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影响因子：
5.7
作者：
Posse, Stefan;Ackley, Elena;Mutihac, Radu;Rick, Jochen;Shane, Matthew;Murray-Krezan, Cristina;Zaitsev, Maxim;Speck, Oliver
通讯作者：
Speck, Oliver
影响因子：
4.8
作者：
Akin, Burak;Lee, Hsu-Lei;LeVan, Pierre
通讯作者：
LeVan, Pierre
影响因子：
4.8
作者：
Uddin, Lucina Q.;Kelly, A. M. Clare;Milham, Michael P.
通讯作者：
Milham, Michael P.
影响因子：
3.7
作者：
Shirer, W. R.;Ryali, S.;Greicius, M. D.
通讯作者：
Greicius, M. D.
影响因子：
3.3
作者：
Grotz, Thimo;Zahneisen, Benjamin;Hennig, Juergen
通讯作者：
Hennig, Juergen