Responsiveness to threat and incentive in bipolar disorder: Relations of the BIS/BAS scales with symptoms
Responsiveness to threat and incentive in bipolar disorder: Relations of the BIS/BAS scales with symptoms
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DOI：
10.1023/a:1010929402770
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发表时间：
2001-09-01
影响因子：
1.6
通讯作者：
Winters, R
中科院分区：
文献类型：
--
作者：
Meyer, B;Johnson, SL;Winters, R
在过去的10年里，理论家认为双相情感障碍症状是由行为激活或促进系统（BAS或BFS）和行为抑制系统（BIS）的活动增加和减少引起的。这些神经行为系统被认为决定了对激励和威胁的情感和行为反应的强度。本研究在59名诊断为双相I型障碍的患者中，对自我报告的BIS和BAS与躁狂和抑郁的横断面和前瞻性关联进行了研究。抑郁症与BIS有关，这表明对抑郁症中威胁的敏感性的重要性。然而，BIS和抑郁症之间的联系似乎依赖于状态。BAS分量表没有相关性与躁狂症状的状态依赖性的方式，但是，BAS（总规模和奖励反应分量表）预测随着时间的推移躁狂症状的相对加剧。因此，有证据表明，BAS敏感性可能构成一个脆弱的躁狂症患者诊断为双相情感障碍。讨论的重点是BIS/BAS结构的整合潜力，将双相情感障碍的社会心理和生物学研究联系起来。
Over the past 10 years, theorists have suggested that bipolar disorder symptoms result from increases and decreases in the activity of the Behavioral Activation or Facilitation System (BAS or BFS) and the Behavioral Inhibition System (BIS). These neurobehavioral systems are thought to determine the intensity of affective and behavioral responses to incentives and threats. This study examined cross-sectional and prospective associations of self-reported BIS and BAS with mania and depression in a sample of 59 individuals diagnosed with Bipolar I disorder. Depression was tied to BIS, pointing to the importance of sensitivity to threats in depression. However, links between BIS and depression appeared state-dependent. BAS subscales did not correlate with manic symptoms in a state-dependent manner; however, BAS (total scale and reward responsiveness subscale) predicted relative intensification of manic symptoms over time. Thus, evidence suggests that BAS sensitivity may constitute a vulnerability to mania among persons diagnosed with bipolar disorder. Discussion focuses on the integrative potential of the BIS/BAS constructs for linking psychosocial and biological research on bipolar disorder.