Dysembryoplastic neuroepithelial tumor with rapid recurrence of pilocytic astrocytoma component.
Dysembryoplastic neuroepithelial tumor with rapid recurrence of pilocytic astrocytoma component.
复制标题
具有毛细胞星形细胞瘤成分快速复发的胚胎发育不良神经上皮肿瘤。
DOI：
10.1007/s10014-013-0155-z
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发表时间：
2013
影响因子：
3.3
通讯作者：
Miyamoto S.
中科院分区：
文献类型：
--
作者：
Takeuchi Y;Arakawa Y;Mikami Y;Matsumoto R;Miyamoto S.
胚胎发育异常神经上皮肿瘤（DNT）很少有复发的侵袭性行为。作者描述了一个快速再生的DNT病例和毛细胞星形细胞瘤的特征。一个19岁的女孩提出了3年的历史复杂的部分癫痫发作，这可能是由于DNT位于左顶叶。肿瘤被切除，但术后14天在MRI上发现一个微小的残余病变，囊性间隙扩大，环形强化，导致再次切除。最终证实复发肿瘤主要由毛细胞星形细胞瘤组成。众所周知，DNT作为一种形态成分不同的肿瘤很少复发，迄今为止文献中尚未报道复发DNT伴快速生长的毛细胞星形细胞瘤的病例。这种现象在复发时可能是组织学上的“替代”。
Dysembryoplastic neuroepithelial tumor (DNT) rarely has aggressive behavior with recurrence. The authors describe a case of DNT with rapid re-growth and features of pilocytic astrocytoma. A 19-year-old girl presented with a 3-year history of complex partial seizure, which was presumably because of DNT located in the left parietal lobe. The tumor was resected, although a tiny residual lesion with cystic space enlarged with ring enhancement identified on MRI 14 days after surgery resulted in re-excision. The recurrent tumor was eventually proved to be predominantly composed of pilocytic astrocytoma. DNT is known to recur only rarely as a tumor with morphologically different components, and no cases of recurrent DNT with rapidly-growing pilocytic astrocytoma have hitherto been reported in the literature. This phenomenon may be histological “replacement” at recurrence.