LEFT-VENTRICULAR FUNCTION IN MEN AND WOMEN - ANOTHER DIFFERENCE BETWEEN SEXES
LEFT-VENTRICULAR FUNCTION IN MEN AND WOMEN - ANOTHER DIFFERENCE BETWEEN SEXES
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DOI：
10.1093/oxfordjournals.eurheartj.a061347
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发表时间：
1982-01-01
影响因子：
39.3
通讯作者：
POPPI, A
中科院分区：
文献类型：
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作者：
BUONANNO, C;ARBUSTINI, E;POPPI, A
在一组 70 名患者中，其中 29 名女性和 41 名男性，胸痛不典型，冠状动脉造影结果正常，测量了左心室功能的一些血流动力学和血管造影参数，目的是确定正常值并记录性别之间可能存在的差异。在舒张参数中，女性左心室舒张末期压力和容积低于男性，LVEDP 为 11.9 ± 3.4 13.7 ± 3.6 mm Hg（P < 0.025），ED V 76.1 ± 15 vs 89.5 ± 23 ml/m2（P < 0.005）。收缩参数中，女性射血分数为 74 ± 7%，显着高于男性 67 ± 7%（P < 0.0005），平均流速也显着高于男性。女性的心室容量减少了 2.59 ± 0.58，而男性的容量减少了 2.26 ± 0.35（P < 0.01）。两性之间的生理多样性，与男性相比，女性表现出持续的高动力状态，心室容量较小，收缩增加，这似乎为女性缺血性心脏病诊断中一些有趣的方面提供了可能的解释。
In a group of 70 patients, 29 women and 41 men, with atypical chest pain and normal findings at coronary arteriography, some hemodynamic and angiographic parameters of left ventricular function were measured, for the purpose of determining the values of normality and to document possible differences between sexes.Of the diastolic parameters, the left ventricular end-diastolic pressure and volume was lower in women than in men, the LVEDP being 11.9 ± 3.4 against 13.7 ± 3.6 mm Hg (P< 0.025), and ED V of 76.1 ± 15 against 89.5 ± 23 ml/m2(P< 0.005).Of the systolic parameters, the ejection fraction of 74 ± 7% in women was significantly higher than that of 67 ± 7% in men (P< 0.0005), and so was the mean velocity of volume reduction of 2.59 ± 0.58 of women against that of 2.26 ± 0.35 of men (P< 0.01).The physiological diversity between the sexes, with women showing a constant hyperdynamic condition in comparison to men, with smaller ventricular volumes and increased contraction, seems to offer a possible explanation for some intriguing aspects of the diagnosis of ischemic heart disease in the female sex.