Acute Ebola virus disease patient treatment and health-related quality of life in health care professionals: A controlled study
Acute Ebola virus disease patient treatment and health-related quality of life in health care professionals: A controlled study
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DOI：
10.1016/j.jpsychores.2015.09.002
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发表时间：
2016-04-01
影响因子：
4.7
通讯作者：
Loewe, Bernd
中科院分区：
文献类型：
--
作者：
Lehmann, Marco;Bruenahl, Christian A.;Loewe, Bernd
目的：本研究旨在确定健康相关的生活质量（HrQoL）的预测因子，并调查在一个埃博拉病毒病（EVD）患者在三级医疗机构的急性治疗发作期间，卫生专业人员感染相关的问题。方法：在一项横断面对照研究中，由三组卫生保健专业人员完成经验证的自我报告问卷：（1）来自三级医疗中心标准内科住院病房的工作人员，（2）来自同一中心负责埃博拉患者治疗的隔离单位的工作人员，以及（3）来自接触埃博拉病毒和其他高传染性病原体的研究实验室的工作人员。结果是HrQoL（SF-12），感染相关的问题，整体健康状况，疲劳（FACIT），抑郁症（PHQ-9），焦虑（GAD-7），和躯体症状（SSS-8）。结果：组间比较（n1 = 42，n2 = 32，n3 = 12），HrQoL，感染的主观风险，和大多数其他社会心理变量没有显着差异。然而，埃博拉患者治疗组的社会隔离程度明显高于其他两组。身体和精神HrQoL较差的最佳预测因素是对埃博拉病毒疾病缺乏了解（身体：B =-1.2，p = 0.05;精神：B =-1.3，p = 0.03）和疲劳（身体：B =-0.3，p = 0.02;精神：B =-0.53，p < 0.001）。埃博拉患者在三级护理中的治疗似乎与较低的HrQoL和感染的主观风险增加无关，但似乎在卫生保健专业人员中产生了社会孤立感。(C)2015 Elsevier Inc. All rights reserved.
Objective: This study aimed to identify predictors of health-related quality of life (HrQoL) and to investigate infection-related concerns in health professionals during the acute treatment episode for one Ebola virus disease (EVD) patient in tertiary care.Methods: In a cross-sectional controlled study, validated self-report questionnaires were completed by three groups of health care professionals: (1) staff from standard internal medicine inpatient wards of a tertiary care center, (2) staff from the isolation unit of the same center responsible for Ebola patient treatment, and (3) staff from a research laboratory with contact to the Ebola virus and other highly infectious pathogens. Outcomes were HrQoL (SF-12), infection-related concerns, global health status, fatigue (FACIT), depression (PHQ-9), anxiety (GAD-7), and somatic symptoms (SSS-8).Results: Comparisons between groups (n1 = 42, n2 = 32, n3 = 12) yielded no significant differences in HrQoL, subjective risk of infection, and most other psychosocial variables. However, the Ebola patient treatment group experienced significantly higher levels of social isolation than both other groups. The best predictors of poor physical and mental HrQoL were perceived lack of knowledge about the Ebola virus disease (physical: B = -1.2, p = 0.05; mental: B = -1.3, p = 0.03) and fatigue (physical: B = -0.3, p = 0.02; mental: B = -0.53, p < 0.001).Conclusion: Ebola patient treatment in tertiary care does not seem to be associated with lower HrQoL and enhanced subjective risk of infection, but seems to yield feelings of social isolation in health-care professionals. (C) 2015 Elsevier Inc. All rights reserved.