What is the criterion for differentiating chronic hepatitis from compensated cirrhosis? A prospective study comparing ultrasonography and percutaneous liver biopsy
What is the criterion for differentiating chronic hepatitis from compensated cirrhosis? A prospective study comparing ultrasonography and percutaneous liver biopsy
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DOI：
10.1016/s0168-8278(97)80140-7
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发表时间：
1997-12-01
影响因子：
25.7
通讯作者：
Bolondi, L
中科院分区：
文献类型：
--
作者：
Gaiani, S;Gramantieri, L;Bolondi, L
背景/目的/方法：目前肝硬化的诊断是基于经皮肝活检，尽管该程序可能会产生假阴性结果。本前瞻性研究对212例经皮肝穿刺活检的代偿性慢性肝病患者进行了超声评分的盲法研究。结果：以活检为标准，超声评分在慢性肝炎（39 ± 33）和肝硬化（100 ± 35）之间有显著性差异（P < 0.05）。
Background/Aims/Methods: The diagnosis of cirrhosis is currently based on percutaneous liver biopsy although this procedure may give rise to false negative results. This prospective study blindly investigates the accuracy of an ultrasonographic score, derived from liver, spleen and portal vein features, in predicting the final diagnosis in 212 patients with compensated chronic liver disease undergoing percutaneous liver biopsy.Results: Taking biopsy as the standard, the ultrasonographic score differed significantly between chronic hepatitis (39+/-33) and cirrhosis (100+/-35) (p