Whole genome analyses reveal weak signatures of population structure and environmentally associated local adaptation in an important North American pollinator, the bumble bee Bombus vosnesenskii
Whole genome analyses reveal weak signatures of population structure and environmentally associated local adaptation in an important North American pollinator, the bumble bee Bombus vosnesenskii
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DOI：
10.1111/mec.17125
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发表时间：
2023-09-13
影响因子：
4.9
通讯作者：
Lozier，Jeffrey D.
中科院分区：
文献类型：
--
作者：
Heraghty，Sam D.;Jackson，Jason M.;Lozier，Jeffrey D.
对在其分布上经历环境异质性的物种的研究已成为了解适应机制和预测对气候变化的反应的重要工具。我们使用分布在广泛纬度和海拔范围的种群的全基因组重测序，研究了美国西部常见的大黄蜂Bombus vosnerenskii的种群结构、人口历史和与环境相关的基因组变异。我们发现， vosensenskii具有最小的群体结构和弱的距离隔离，这证实了以前使用其他分子标记类型的研究结果。同样，使用顺序马尔科夫合并模型进行的人口分析表明，最小的种群结构可能自上一次间冰期以来一直存在，物种范围不同部分的基因组显示出类似的历史有效种群规模轨迹，并且随时间的波动相对较小。冗余度分析揭示了由生物气候变量解释的少量基因组变异。潜在因子混合模型的环境关联分析(LFMM2)发现了稀疏分布在基因组中的几个离群点，尽管识别了一些假定的选择性扫描特征，但没有一个包含特别大量的基因座。一些离群点位于已知调控关系的基因中，这表明存在弱选择的可能性，尽管与用类似方法检查的其他物种相比，基因组中存在广泛的局部适应特征的证据相对较弱。总体而言，结果表明B. vosnerenskii是一个在其环境要求方面具有高度灵活性的多面手的例子，这可能最终使该物种在气候变化期受益。
Studies of species that experience environmental heterogeneity across their distributions have become an important tool for understanding mechanisms of adaptation and predicting responses to climate change. We examine population structure, demographic history and environmentally associated genomic variation inBombus vosnesenskii, a common bumble bee in the western USA, using whole genome resequencing of populations distributed across a broad range of latitudes and elevations. We find thatB. vosnesenskiiexhibits minimal population structure and weak isolation by distance, confirming results from previous studies using other molecular marker types. Similarly, demographic analyses with Sequentially Markovian Coalescent models suggest that minimal population structure may have persisted since the last interglacial period, with genomes from different parts of the species range showing similar historical effective population size trajectories and relatively small fluctuations through time. Redundancy analysis revealed a small amount of genomic variation explained by bioclimatic variables. Environmental association analysis with latent factor mixed modelling (LFMM2) identified few outlier loci that were sparsely distributed throughout the genome and although a few putative signatures of selective sweeps were identified, none encompassed particularly large numbers of loci. Some outlier loci were in genes with known regulatory relationships, suggesting the possibility of weak selection, although compared with other species examined with similar approaches, evidence for extensive local adaptation signatures in the genome was relatively weak. Overall, results indicateB. vosnesenskiiis an example of a generalist with a high degree of flexibility in its environmental requirements that may ultimately benefit the species under periods of climate change.