Compared effects of surgical and natural menopause on climacteric symptoms, osteoporosis, and metabolic syndrome

Compared effects of surgical and natural menopause on climacteric symptoms, osteoporosis, and metabolic syndrome
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DOI:
10.1016/j.ijgo.2009.03.016
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发表时间:
2009-07-01
影响因子:
3.8
通讯作者:
Kaya, Bugra
Kaya, Bugra
中科院分区:
医学4区
文献类型:
--
作者:
Ozdemir, Suna;Celik, Cetin;Kaya, Bugra

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目的:比较手术(即早绝经)和自然绝经(即晚绝经)对更年期症状骨质疏松症的影响。和代谢综合症。方法:对94例接受子宫切除和双侧卵巢切除的妇女和95例40岁以上自然绝经的妇女进行研究。没有人接受过激素治疗或骨质疏松症治疗。结果:更年期手术组潮热(P=0.001)、出汗(P=0.001)、记忆力减退(P=0.04)、性欲改变(P=0.04)、骨质疏松症(诊断为髋部骨质疏松症,P=0.005)的发生率明显高于手术组,但两组代谢综合征发生率相似(47.8%和40%;P=0.28)。结论:手术绝经与自然绝经相比,更年期症状和骨质疏松症的发生率较高,而代谢综合征的发生率较低。皇冠版权(C)2009由爱思唯尔爱尔兰有限公司代表国际妇产科联合会出版。版权所有。
Objective: To compare the effects of surgical (ie, earlier) and natural (ie, later) menopause oil climacteric symptoms, osteoporosis. and metabolic syndrome. Method: The study was conducted with 94 women who underwent hysterectomy and bilateral oophorectomy and 95 women who were older than 40 years and in natural menopause. None had received hormone theraphy or osteoporosis treatment. Metabolic syndrome was defined according to the National Cholesterol Education Program Adult Treatment Panel III. Results: The rates of hot flushes (P=0.001), sweating (P=0.001), poor memory (P=0.04), change in sexual desire (P=0.04), and osteoprosis (diagnosed in the hip bone, P=0.005) were significantly higher among the women in Surgical menopause, but the rate of metabolic syndrome was similar in the 2 groups (47.8% and 40%; P=0.28). Conclusion: Compared with natural menopause, surgical menopause was found to be associated with highter rates of climacteric symptoms and osteoporosis but not of of metabolic syndrome. Crown Copyright (C) 2009 Published by Elsevier Ireland Ltd. on behalf of International Federation of Gynecology and Obstetrics. All rights reserved.