Mathematical models of sleep regulation
Mathematical models of sleep regulation
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DOI：
10.2741/1064
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发表时间：
2003-05-01
影响因子：
3.1
通讯作者：
Borbély, AA
中科院分区：
文献类型：
--
作者：
Achermann, P;Borbély, AA
EEG慢波活动（SWA）的水平由先前睡眠和清醒的持续时间决定。SWA是非快速眼动睡眠强度的标志物，可以作为睡眠稳态的指标。睡眠调节的双过程模型假定了稳态过程S和昼夜节律过程C的相互作用。神经行为功能的模型（三过程模型;警觉性和认知吞吐量的交互模型）也是基于稳态和昼夜因素之间相互作用的概念。这种相互作用究竟是线性的还是非线性的，目前还没有定论。模型可以作为一个指导原则，用于指定在宏观和微观分析水平上发生的过程之间的关系。
The level of EEG slow-wave activity ( SWA) is determined by the duration of prior sleep and waking. SWA is a marker of nonREM sleep intensity and may serve as an indicator of sleep homeostasis. The two-process model of sleep regulation posits the interaction of the homeostatic Process S and the circadian Process C. Also models of neurobehavioral functions (three-process model; interactive models of alertness and cognitive throughput) are based on the concept of an interaction between homeostatic and circadian factors. Whether the interaction is linear or nonlinear is still unresolved. Models may serve as a guiding principle for specifying the relationship between processes occurring at the macroscopic and microscopic level of analysis.