Exploring research frontiers in microbiology: the challenge of metagenomics in soil microbiology
Exploring research frontiers in microbiology: the challenge of metagenomics in soil microbiology
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DOI：
10.1016/j.resmic.2010.04.010
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发表时间：
2010-07-01
影响因子：
2.6
通讯作者：
Benedetti, Anna
中科院分区：
文献类型：
--
作者：
Mocali, Stefano;Benedetti, Anna
土壤是微生物学家最复杂和最具挑战性的环境之一。事实上，尽管它包含了地球上最大的微生物多样性，但这些微生物中的大多数仍然没有被描述，并且代表了一个巨大的未开发的遗传和代谢多样性库。宏基因组学是对土壤生物群全基因组的研究，目前是评估复杂微生物群落多样性的一个有力工具，提供了获得与生物技术和农业应用有关的一些新物种、基因或新分子的途径。在本文中，新的高通量宏基因组方法和土壤微生物生态学和数据处理的新观点的开始进行了讨论。(C)2010年Elsevier Masson SAS。All rights reserved.
Soil is one of the most complex and challenging environments for microbiologists. In fact, although it contains the largest microbial diversity on the planet, the majority of these microbes are still uncharacterized and represent an enormous unexplored reservoir of genetic and metabolic diversity. Metagenomics, the study of the entire genome of soil biota, currently represents a powerful tool for assessing the diversity of complex microbial communities, providing access to a number of new species, genes or novel molecules that are relevant for biotechnology and agricultural applications. In this paper, the onset of new high-throughput metagenomic approaches and new perspectives in soil microbial ecology and data handling are discussed. (C) 2010 Elsevier Masson SAS. All rights reserved.