Phototriggers for nucleobases with improved photochemical properties
Phototriggers for nucleobases with improved photochemical properties
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DOI：
10.1021/ol702106t
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发表时间：
2007-11-08
期刊：
影响因子：
5.2
通讯作者：
Matsuba, Chie
中科院分区：
文献类型：
--
作者：
Furuta, Toshiaki;Watanabe, Takayoshi;Matsuba, Chie
介绍了新型光可去除的碱基保护基的合成及其光化学性质。合成了4个笼状2 '-脱氧胞苷（dCs），并在模拟生理条件下测定了它们的光化学性质。两个新的香豆素笼DC表现出更好的光化学和光物理性能比那些笼DC有以前报道的笼组。
Synthesis and photochemical properties of new photoremovable protecting groups for nucleobases are described. Four caged 2'-deoxycytidines (dCs) were synthesized, and their photochemical properties were measured under simulated physiological conditions. Two new coumarin-caged dCs show better photochemical and photophysical properties than those of the caged dCs having previously reported caging groups.