Association between sleep disturbances, fear of hypoglycemia and psychological well-being in adults with type 1 diabetes mellitus, data from cross-sectional VARDIA study
Association between sleep disturbances, fear of hypoglycemia and psychological well-being in adults with type 1 diabetes mellitus, data from cross-sectional VARDIA study
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DOI：
10.1016/j.diabres.2019.107988
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发表时间：
2020-02-01
影响因子：
5.1
通讯作者：
Briet, Claire
中科院分区：
文献类型：
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作者：
Suteau, Valentine;Saulnier, Pierre-Jean;Briet, Claire
目的：评估 1 型糖尿病患者的睡眠质量、对低血糖的恐惧、血糖变异性和心理健康之间的关系。方法：我们的数据由 VARDIA 研究提供，该研究是 2015 年 6 月至 12 月进行的一项多中心横断面研究。睡眠特征通过匹兹堡睡眠质量指数 (PSQI) 进行评估。对低血糖的恐惧和心理健康分别通过低血糖恐惧调查第二版（HFS-II）和医院焦虑和抑郁量表（HADS）来测量。使用三个 7 点自我监测血糖曲线的 CV 和血糖波动的平均幅度 (MAGE) 确定血糖变异性 (GV)。 结果：315 名患者符合 PSQI 问卷分析的条件：54% 为女性，平均年龄 47 +/- 15，平均糖尿病病程 24 +/- 13 年，HbA1c 为 7.6 +/- 0.9% (60 +/- 0.9%) 7.5毫摩尔/摩尔）。平均 PSQI 评分为 6.0 +/- 3.3，59.8% 的患者 PSQI 评分 > 5。“睡眠质量差”者的 HFS-II 评分和 HADS 显着较高 (p < 0.0001)，PSQI 评分与 HADS 呈正相关 (b = 0.22; 95% CI = 0.08;0.35)。通过 CV 或 MAGE 评估的 GV 在“较差”和“良好”睡眠者之间没有差异（分别为 p = 0.28 和 0.54）。结论：成年 1 型糖尿病患者存在与心理健康相关的睡眠障碍。这项研究表明，心理管理可以成为改善 1 型糖尿病成人睡眠质量的目标。 (C) 2019 Elsevier B.V. 保留所有权利。
Aim: To assess the relationship between sleep quality, fear of hypoglycemia, glycemic variability and psychological well-being in type 1 diabetes mellitus.Methods: Our data were provided by the VARDIA Study, a multicentric cross-sectional study conducted between June and December 2015. Sleep characteristics were assessed by the Pittsburgh Sleep Quality Index (PSQI). Fear of hypoglycemia and psychological well-being were measured with the Hypoglycemia Fear Survey version II (HFS-II) and the Hospital Anxiety and Depression Scale (HADS), respectively. Glycemic variability (GV) was determined using the CV of three 7-point self-monitoring blood glucose profiles and the mean amplitude of glycemic excursion (MAGE).Results: 315 patients were eligible for PSQI questionnaire analysis: 54% women, mean age 47 +/- 15, mean diabetes duration of 24 +/- 13 years, HbA1c of 7.6 +/- 0.9% (60 +/- 7,5mmol/mol). Average PSQI score was 6.0 +/- 3.3 and 59.8% of the patients had a PSQI score > 5. HFS-II score and HADS were significantly higher among "poor" sleepers (p < 0.0001) and PSQI score was positively associated with HADS (b = 0.22; 95% CI = 0.08;0.35). GV evaluated by CV or MAGE did not differ between "poor" and "good" sleepers (p = 0.28 and 0.54, respectively).Conclusions: Adult patients with type 1 diabetes have sleep disturbances which correlate with psychological well-being. This study suggests that psychological management can be a target to improve sleep quality in adults with type 1 diabetes mellitus. (C) 2019 Elsevier B.V. All rights reserved.