Relationship Between Olfactory Disturbance After Acute Ischemic Stroke and Latent Thalamic Hypoperfusion.
Relationship Between Olfactory Disturbance After Acute Ischemic Stroke and Latent Thalamic Hypoperfusion.
复制标题
急性缺血性中风后嗅觉障碍与潜在丘脑灌注不足之间的关系。
DOI：
10.1093/chemse/bjz077
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发表时间：
2020
期刊：
影响因子：
3.5
通讯作者：
Miwa T.
中科院分区：
文献类型：
--
作者：
Okamoto K;Shiga H;Nakamura H;Matsui M;Miwa T.
对19例急性缺血性中风患者的气味检测、识别和鉴定进行了评估，这些患者没有核磁共振成像可检测到的丘脑病变，但99m-乙基半胱氨酸二聚体单光子发射断层扫描显示丘脑低灌注量。尽管这些患者没有意识到嗅觉功能的下降，但他们在气味识别和识别阈值测试中的得分明显低于9名丘脑灌注量正常的缺血性中风对照组。然而，两组的绝对气味检测阈值相似。这些结果证明了脑灌注核素显像在评估缺血性中风后感觉丧失方面的有效性，并为丘脑在嗅觉中的作用提供了进一步的证据。
Odor detection, recognition, and identification were assessed in 19 acute ischemic stroke patients who had no magnetic resonance imaging-detectable thalamic lesions but in whom technetium-99m ethyl cysteinate dimer single photon emission tomography revealed thalamic hypoperfusion. Although these patients were unaware of reduced olfactory function, they exhibited significantly lower scores in tests for odor identification and recognition threshold as compared with 9 ischemic stroke controls that had normal thalamic hypoperfusion. However, absolute odor detection thresholds were similar in the 2 groups. These results demonstrate the usefulness of cerebral perfusion scintigraphy in assessing sensory loss after ischemic stroke and provide further evidence for the role of the thalamus in olfaction.