An update on the role of the microbiome in non-alcoholic fatty liver disease pathogenesis, diagnosis, and treatment.

An update on the role of the microbiome in non-alcoholic fatty liver disease pathogenesis, diagnosis, and treatment.
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DOI:
10.1007/s11938-020-00290-2
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发表时间:
2020-06
期刊:
Current treatment options in gastroenterology
影响因子:
--
通讯作者:
Loomba R
Loomba R
中科院分区:
其他
文献类型:
--
作者:
Mouzaki M;Loomba R

文献摘要

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当NAFLD中的生态失调的第一个研究被报道时,微生物组最初被假定为有助于NAFLD的发病机制。从那时起,许多研究进一步调查了这一发现,以辨别生态失调是NAFLD中观察到的代谢失调的结果还是该疾病发病机制的促成因素。
The microbiome was originally postulated to contribute to the pathogenesis of NAFLD when the first studies of dysbiosis in NAFLD were reported. Since then, a number of studies have investigated this finding further, in order to discern whether the dysbiosis is the result of the metabolic dysregulation seen with NAFLD or a contributor to the pathogenesis of this condition.