Suzuki coupling for protein modification
Suzuki coupling for protein modification
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DOI：
10.1016/j.tetlet.2005.03.094
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发表时间：
2005-05-09
影响因子：
1.8
通讯作者：
Hamachi, I
中科院分区：
文献类型：
--
作者：
Ojida, A;Tsutsumi, H;Hamachi, I
Suzuki偶联反应是小分子间的典型交叉偶联反应，可在温和的水溶液Linder条件下在蛋白质表面进行。通过偶联反应产生的修饰蛋白保持其天然的结构和功能。此外，荧光染料附加蛋白质作为一种荧光生物传感器。(c)2005爱思唯尔有限公司保留所有权利。
Suzuki-coupling, a representative cross-coupling reaction between small molecules, can proceed on a protein surface in aqueous Solution Linder mild conditions. The modified protein produced by the coupling reaction maintained its native like structure and function. In addition, fluorescent dye appended-protein acts as a fluorescent biosensor. (c) 2005 Elsevier Ltd. All rights reserved.