A Novel Congenital Cataract Category System Based on Lens Opacity Locations and Relevant Anterior Segment Characteristics
A Novel Congenital Cataract Category System Based on Lens Opacity Locations and Relevant Anterior Segment Characteristics
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基于晶状体混浊位置和相关眼前节特征的新型先天性白内障分类系统。
DOI：
10.1167/iovs.16-20280
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发表时间：
2016-11-01
影响因子：
4.4
通讯作者：
Liu, Yizhi
中科院分区：
文献类型：
--
作者：
Lin, Haotian;Lin, Duoru;Liu, Yizhi
目的。目的比较先天性白内障(CC)患者晶状体不同部位混浊的眼前段特征，提出一种改良的、简单的CC分类系统。方法：根据裂隙灯检查晶状体混浊的位置和三维眼前段成像系统，将CC患者的白内障分为四组：全白内障、前白内障、内白内障和后发性白内障。结果：对428例CC患者的平均角膜屈光度、角膜散光(CA)、中央角膜厚度(CCT)和前房深度(ACD)进行了比较。前部白内障的患者中有一半出现了瞳孔残留膜的并发症。后发性白内障中90.38%为单眼受累。全白内障、前白内障或内白内障患者的角膜屈光度值大于后白内障或透明晶状体患者。先天性白内障患者的CA和CCT值高于晶状体清晰者。前部白内障患者CA最大，随着晶状体后方混浊部位的增多，CA值逐渐减小。全眼和前段白内障ACDs较小，内段和后段白内障ACDs较晶状体清晰眼大。结论CC合并不同部位晶状体混浊患者的ACDs具有不同的眼前段特征。根据晶状体混浊的位置与眼前段特征之间的关系，改进的CC分类系统可能有利于CC的诊断和治疗。
PURPOSE. We compared the anterior segment characteristics of congenital cataract (CC) patients with lens opacities in different locations and proposed a modified, simple CC category system.METHODS. Cataractous eyes of CC patients were classified into four groups based on the locations of lens opacities shown in slit-lamp examinations and by a 3-dimensional anterior segment imaging system as follows: total, anterior, interior, and posterior cataracts. The mean keratometry value, corneal astigmatism (CA), central corneal thickness (CCT), and anterior chamber depth (ACD) of eyes in different groups were compared.RESULTS. We included a total of 428 CC patients. Half of the patients with an anterior cataract had the complication of a pupillary residual membrane. Among the patients with posterior lentiglobus cataracts, 90.38% had unilateral involvement. Patients with total, anterior, or interior cataracts had larger keratometry values than those with either posterior cataracts or clear lens. Congenital cataract patients had greater CA and CCT values than those with a clear lens. The largest CA was presented in patients with anterior cataracts, and the value decreased gradually with more posterior locations of lens opacities. Eyes with total and anterior cataracts had smaller ACDs, and eyes with interior and posterior cataracts had greater ACDs than eyes with a clear lens.CONCLUSIONS. Cataractous eyes in CC patients with lens opacities in different locations presented distinct anterior segment characteristics. The modified CC category system, based on the relationships among the locations of lens opacities and anterior segment characteristics, may be beneficial for CC diagnosis and treatment.