Psychosocial factors associated with adherence to antiretroviral medications in a sample of HIV-positive African American drug users
Psychosocial factors associated with adherence to antiretroviral medications in a sample of HIV-positive African American drug users
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DOI：
10.1080/09540120410001683394
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发表时间：
2004-04-01
影响因子：
1.7
通讯作者：
Keel, KB
中科院分区：
文献类型：
--
作者：
Harzke, AJ;Williams, ML;Keel, KB
这项研究的目的是调查影响非裔美国人吸毒者抗逆转录病毒依从性的因素，特别是确定自我报告的依从性水平与根据压力和应对交易模型(TMSC)选择的心理社会措施之间的联系。这项研究使用了从137名艾滋病毒阳性非裔美国人吸毒者那里收集的数据，这些吸毒者在接受采访时正在接受抗逆转录病毒药物治疗。使用相关分析研究了两个变量的相关性，并将与依从性显著相关的变量输入到多元回归模型中。多变量模型只显示了抗逆转录病毒药物的感知有效性，而感知障碍的一种衡量标准，即简单地忘记服药，与依从性独立相关。这些初步发现表明，理解抗逆转录病毒依从性的理论方法必须解决一系列变量，包括但不限于行为实践、认知评估、情感反应和社会支持。建议使用完整的TMSC进行进一步研究。
The purpose of the study was to investigate factors affecting antiretroviral adherence among African American drug users, specifically to identify associations between self-reported adherence levels and psychosocial measures selected with guidance from the Transactional Model of Stress and Coping (TMSC). The study was conducted using data collected from 137 HIV-positive African American drug users who were receiving antiretroviral medications at the time they were interviewed. Bivariate associations were investigated using correlational analyses and variables showing a significant correlation with adherence were entered into a multivariate regression model. The multivariate model showed only perceived efficacy of antiretrovirals and one measure of perceived barriers, simply forgetting to take medications, were independently related to adherence. These preliminary findings suggest that theoretical approaches to understanding antiretroviral adherence must address a range of variables, including but not limited to behavioural practices, cognitive appraisals, affective responses and social support. Further studies using the complete TMSC are recommended.