Functionalization and metathesis polymerization induced self-assembly of an alternating copolymer into giant vesicles.
Functionalization and metathesis polymerization induced self-assembly of an alternating copolymer into giant vesicles.
复制标题
官能化和复分解聚合诱导交替共聚物自组装成巨型囊泡
DOI：
10.1039/d1ra00835h
复制
发表时间：
2021-04-21
期刊：
影响因子：
3.9
通讯作者：
Li X
中科院分区：
文献类型：
--
作者：
Song W;Shen J;Li X
研究了无环二烯易位聚合（ADMET）和交替易位聚合（ALTMET）制备球形囊泡和胶束的方法。我们利用氟（FL）和基于二萘嵌苯二酰亚胺（PDI）的α，ω-二烯和α，ω-二丙烯酸酯来提供一系列均聚物和交替共聚物。当使用α，ω-二烯作为模型单体时，TEM测量表明芳香族FL和PDI结构单元诱导聚合物产生中等尺寸（分别为30-50 nm和90-120 nm）的胶束和囊泡。令人惊讶的是，由PDI α，ω-二烯和FL α，ω-二丙烯酸酯衍生的交替共聚物自发地形成尺寸在0.7 μm至2.5 μm范围内的巨大囊泡。通过ADMET和ALTMET技术介导的有机聚合物的受控自组装避免了极其恼人的后处理。因此，这项工作建立了一种新的，通用的合成策略，以创建具有可调形态的纳米颗粒，具有作为分子有效载荷递送载体的潜在应用。以含氟（FL）和苝酰亚胺（PDI）为单体，合成了一系列均聚物和交替共聚物，并通过复分解聚合得到了球形囊泡和胶束。
A facile fabrication of spherical vesicles and micelles by acyclic diene metathesis (ADMET) polymerization and alternative metathesis polymerization (ALTMET) was investigated. We utilize fluorine (FL) and perylene diimide-based (PDI) α,ω-dienes and α,ω-diacrylates to provide a series of homopolymers and alternating copolymers. When using α,ω-dienes as model monomers, TEM measurement indicates that the aromatic FL and PDI building block induced polymers to generate medium-sized (30–50 nm and 90–120 nm, respectively) micelles and vesicles. It was amazing that alternating copolymers derived from PDI α,ω-dienes and FL α,ω-diacrylates spontaneously form giant vesicles with sizes in the range of 0.7 μm to 2.5 μm. The controlled self-assembly of the organic polymer mediated by ADMET and ALTMET techniques avoided extremely annoying post treatment. Therefore, this work establishes a new, versatile synthetic strategy to create nanoparticles having tunable morphologies with potential application as molecular payload delivery vehicles. Fluorine (FL) and perylene diimide-based (PDI) α,ω-dienes and α,ω-diacrylates were used to synthesise a series of homopolymers and alternating copolymers and provide spherical vesicles and micelles by metathesis polymerization.
登录
查看更多内容
影响因子：
15
作者：
Jin, W;Fukushima, T;Aida, T
通讯作者：
Aida, T
影响因子：
7.015
作者：
Lotierzo, Andrea;Schofield, Ryan M.;Bon, Stefan A. F.
通讯作者：
Bon, Stefan A. F.
影响因子：
5.5
作者：
Lv, An;Li, Zi-Long;Li, Zi-Chen
通讯作者：
Li, Zi-Chen
影响因子：
7.015
作者：
Schulz, Michael D.;Wagener, Kenneth B.
通讯作者：
Wagener, Kenneth B.
探究均聚物自组装：氢键如何影响形态？
影响因子：
5.5
作者：
Zhu, Yunqing;Liu, Lin;Du, Jianzhong
通讯作者：
Du, Jianzhong