Rituximab for non-responsive idiopathic membranous nephropathy in a Chinese cohort

Rituximab for non-responsive idiopathic membranous nephropathy in a Chinese cohort
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利妥昔单抗治疗中国队列中的无反应特发性膜性肾病。

DOI:
10.1093/ndt/gfx295
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发表时间:
2018-09-01
影响因子:
6.1
通讯作者:
Zhao, Ming-Hui
Zhao, Ming-Hui
中科院分区:
医学1区
文献类型:
--
作者:
Wang, Xin;Cui, Zhao;Zhao, Ming-Hui

文献摘要

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Background. Rituximab had been shown to be effective in inducing remission of nephrotic syndrome in patients with idiopathic membranous nephropathy (iMN). This study applied rituximab therapy for 36 non-responsive iMN patients to investigate its effects and safety.Methods. Thirty-six iMN patients who were non-responsive to prior immunosuppression were enrolled. Rituximab was used for B-cell depletion in patients, with a goal of