Time-frequency spectral analysis of heart rate variability during induction of general anaesthesia

Time-frequency spectral analysis of heart rate variability during induction of general anaesthesia
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DOI:
10.1093/bja/79.6.754
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发表时间:
1997-12-01
影响因子:
9.8
通讯作者:
Huang, CH
Huang, CH
中科院分区:
医学1区
文献类型:
--
作者:
Huang, HH;Chan, HL;Huang, CH

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我们检测了硫喷妥钠麻醉诱导、气管插管和随后吸入异氟醚-一氧化二氮期间心率变异性(HRV)的频谱成分。常用的频谱分析方法,如快速傅立叶变换或自回归模型,需要平稳的数据,不适用于这一时期快速变化的心率变异性数据。研究中使用了一种先进的谱分析方法--时频分析,它可以处理非平稳数据。生成多个频谱以显示HRV随时间变化的频谱分量。计算并比较基线、诱导后(插管前)、插管后即刻和维持期的中频功率(MF,0.08~0.15 Hz)、高频功率(HF,0.15~0.5 Hz)和MF/HF比值。中频和高频功率在诱导后下降,在维持期进一步降低,但中频/高频比值在诱导后保持不变。插管后即刻中频功率和高频功率与插管前无显著差异,但中频/高频比值与插管前相比有显著差异。
We have examined the spectral components of heart rate variability (HRV) during induction of anaesthesia with thiopentone, tracheal intubation and subsequent inhalation of isoflurane-nitrous oxide. Commonly used spectral analysis methods such as fast Fourier transformation or autoregressive modelling require stationary data and are not suitable for the rapidly changing HRV data in this period. An advanced spectral analysis method, time-frequency analysis, which can treat non-stationary data, was used in this study. Multiple spectra were generated to demonstrate the time-related spectral components of HRV. Mid-frequency power (MF, 0.08-0.15 Hz), high-frequency power (HF, 0.15-0.5 Hz) and MF/HF ratio at baseline, after induction (before intubation), immediately after intubation and during maintenance periods were calculated and compared. MF and HF powers decreased after induction and were reduced further in the maintenance period but MF/HF ratio remained unchanged after induction. Immediately after intubation MF and HF powers did not differ significantly from the immediate pre-intubation values, but MF/HF ratio did.