On the possibility of silicon nitride as a ceramic for structural orthopaedic implants. Part I: processing, microstructure, mechanical properties, cytotoxicity
On the possibility of silicon nitride as a ceramic for structural orthopaedic implants. Part I: processing, microstructure, mechanical properties, cytotoxicity
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DOI：
10.1007/s10856-008-3417-2
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发表时间：
2008-08-01
影响因子：
3.7
通讯作者：
Bellosi, Alida
中科院分区：
文献类型：
--
作者：
Mazzocchi, Mauro;Bellosi, Alida
尽管氮化硅具有良好的机械和摩擦学性能，但其作为骨重建或关节置换假体的适用性仍存在争议。本研究旨在设计并制备三种不同的氮化硅基陶瓷，并对材料进行测试。在第I部分中，微观结构和机械性能证明了突出的特性，细胞毒性研究证实所有材料均具有极强的惰性和生物相容性。在第二部分中，对不同的水介质和生理溶液的磨损性能和润湿性和化学稳定性进行了研究和讨论。
Notwithstanding the good combination of mechanical and tribological properties, the suitability of silicon nitride for application as prosthesis in bone reconstruction or in articular joints replacements is still controversial. This study aims to design and produce three different silicon nitride-based ceramics and to test the materials. In this Part I the microstructure and mechanical properties evidence outstanding characteristics and the cytotoxicity studies confirm that all the materials are extremely inert and biocompatible. In Part II, the wear performance and the wettability and chemical stability against different aqueous media and physiological solutions are investigated and discussed.