Changing Demographics, Epidemiology, and Survival of Incident Pulmonary Arterial Hypertension Results from the Pulmonary Hypertension Registry of the United Kingdom and Ireland
Changing Demographics, Epidemiology, and Survival of Incident Pulmonary Arterial Hypertension Results from the Pulmonary Hypertension Registry of the United Kingdom and Ireland
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DOI：
10.1164/rccm.201203-0383oc
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发表时间：
2012-10-15
影响因子：
24.7
通讯作者：
Peacock, Andrew J.
中科院分区：
文献类型：
--
作者：
Ling, Yi;Johnson, Martin K.;Peacock, Andrew J.
Rationale: Incident pulmonary arterial hypertension was underrepresented in most pulmonary hypertension registries and may have a different disease profile to prevalent disease.Objectives: To determine the characteristics and outcome of a purely incident, treatment-naive cohort of idiopathic, heritable, and anorexigen-associated pulmonary arterial hypertension and to determine the changes in presentations and survival over the past decade in the United Kingdom and Ireland.Methods: All consecutive newly diagnosed patients from 2001 to 2009 were identified prospectively.Measurements and Main Results: A total of 482 patients (93% idiopathic, 5% heritable, and 2% anorexigen-associated pulmonary arterial hypertension) were diagnosed, giving rise to an estimated incidence of 1.1 cases per million peryear and prevalence of 6.6 cases per million in 2009. Younger patients (age
