Clinical, radiographic and histologic analysis of the effects of pulp capping materials used in pulpotomies of human primary teeth
Clinical, radiographic and histologic analysis of the effects of pulp capping materials used in pulpotomies of human primary teeth
复制标题
DOI：
10.1007/s40368-013-0015-x
复制
发表时间：
2013-04-01
影响因子：
2.2
通讯作者：
Abdo, R. C. C.
中科院分区：
文献类型：
--
作者：
Oliveira, T. M.;Moretti, A. B. S.;Abdo, R. C. C.
目的比较三氧化矿物聚合物（MTA）、氢氧化钙（CH）和波特兰水泥（PC）作为活髓切断剂对人乳磨牙牙髓的临床、影像学和组织学反应。研究设计45颗下颌乳磨牙随机分为CH、MTA和PC组，采用传统的活髓切断技术进行治疗。不同之处仅在于每组的封盖材料。在6个月、12个月和24个月随访时记录临床和影像学评价。定期剥脱期的牙齿进行进一步的组织学分析。统计学使用参数检验在5%的显著性水平下检验数据。结果MTA组和PC组在6、12和24个月的临床和影像学上均显示100%的成功率。在CH组中，在整个随访期间检测到几颗牙齿出现临床和放射学失败，内吸收是常见的放射学发现。组织学分析显示，PC和MTA组中存在牙本质样矿化物质沉积，闭塞了根管。结论MTA和PC可作为乳牙活髓切断术的有效材料。虽然我们的结果是非常令人鼓舞的，但需要进一步的研究和更长的随访评估，以确定波特兰水泥的安全临床适应症。
Aim To compare the clinical, radiographic and histological responses of the pulp to mineral trioxide aggregate (MTA), calcium hydroxide (CH) and Portland cement (PC) when used as a pulpotomy agent in human primary teeth.Study design Forty-five mandibular primary molar teeth were randomly assigned to CH, MTA or PC groups and treated by pulpotomy technique.Methods The teeth were treated by conventional pulpotomy technique, differing only in the capping material for each group. Clinical and radiographic evaluations were recorded at 6-, 12- and 24-month follow-up. Teeth in the regular exfoliation period were further processed for histologic analysis. Statistics Data were tested using parametric tests at a significance level of 5 %. The histological results were expressed descriptively.Results Clinically and radiographically, the MTA and PC groups showed 100 % success rates at 6, 12 and 24 months. In CH group, several teeth presented clinical and radiographic failures detected throughout the followup period, and internal resorption was a frequent radiographic finding. Histologic analysis revealed the presence of dentine-like mineralised material deposition obliterating the root canal in the PC and MTA groups. CH group presented, in most of the sections, necrotic areas in the root canals.Conclusions MTA and PC may serve as effective materials for pulpotomies of primary teeth as compared to CH. Although our results are very encouraging, further studies and longer follow-up assessments are needed in order to determine the safe clinical indication of Portland cement.