Erythrina alkaloids and a pterocarpan from the bark of Erythrina subumbrans
Erythrina alkaloids and a pterocarpan from the bark of Erythrina subumbrans
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DOI：
10.1021/np070506w
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发表时间：
2008-01-01
影响因子：
5.1
通讯作者：
Suksamram, Apichart
中科院分区：
文献类型：
--
作者：
Rukachaisirikul, Thitima;Innok, Phongsak;Suksamram, Apichart
报道了三种新的红景天属生物碱：(+)-10，11-二氧代红景天碱(1)，(+)-10，11-二氧代表没食子酸(2)和(+)-10，11-二氧代红景天碱(3)。从刺五加树皮中分离得到一个新的蕨类化合物1-甲氧基红景天素II(4)，以及7个已知的蕨类化合物：红景天素II、红景天素A、麦冬红素A、红景天素-1、红景天素A和羟基红景天，3个黄烷酮5-羟基苦参素、苦参酮V和胡枝子黄素B，3个三萜类、苦参二醇、大豆皂苷元B和芦荟素C，根据波谱数据鉴定了它们的结构。对一些分离株进行了抗疟原虫、抗分枝杆菌和细胞毒活性测试。
Three new erythrina alkaloids, (+)-10,11-dioxoerythratine (1), (+)-10,11-dioxoepierythratidine (2), and (+)-10,11-dioxoerythratidinone (3). and a new pterocarpan, 1-methoxyerythrabyssin II (4), were isolated from the bark of Erythrina subumbrans, together with seven known pterocarpans, erythrabyssin II, erybraedin A, erystagallin A, erycristagallin, erythrabissin-1, eryvarin A, and hydroxycristacarpone, three flavanones, 5-hydroxysophoranone, abyssinone V, and lespedezaflavanone B, three triterpenes, sophoradiol, soyasapogenol B, and lupeol, and one isoflavanone, vogelin C. Their structures were elucidated on the basis of spectroscopic data. Some isolates were tested for antiplasmodial, antimycobacterial, and cytotoxic activities.