Why is the effect of malaria parasites on mosquito survival still unresolved?

Why is the effect of malaria parasites on mosquito survival still unresolved?
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DOI:
10.1016/s1471-4922(02)02281-x
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发表时间:
2002-06-01
影响因子:
9.6
通讯作者:
Read, AF
Read, AF
中科院分区:
医学1区
文献类型:
--
作者:
Ferguson, HM;Read, AF

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尽管经过了近一个世纪的努力,疟疾寄生虫是否会杀死蚊子媒介的问题仍然悬而未决。一些对感染和未感染蚊子寿命的直接比较发现了疟疾导致的死亡,而另一些则没有。在这里,我们使用荟萃分析来表明,总的来说,疟疾寄生虫确实降低了蚊子的存活率。然而,在非自然病媒-寄生虫组合和持续时间较长的研究中,更有可能检测到死亡影响。除非对这些因素进行系统的调查,否则不可能得出明确的结论。
Despite almost a century of effort, the question of whether malaria parasites kill their mosquito vectors remains open. Some direct comparisons of the longevity of infected and uninfected mosquitoes have found malaria-induced mortality, whereas others have not. Here, we use meta-analysis to show that, overall, malaria parasites do reduce mosquito survival. However, mortality effects are more likely to be detected in unnatural vector-parasite combinations and in studies of longer duration. Until these factors are systematically investigated, no firm generalities are possible.