Ancient Jomon genome sequence analysis sheds light on migration patterns of early East Asian populations
Ancient Jomon genome sequence analysis sheds light on migration patterns of early East Asian populations
复制标题
DOI：
10.1038/s42003-020-01162-2
复制
发表时间：
2020-08-25
影响因子：
5.9
通讯作者：
Oota, Hiroki
中科院分区：
文献类型：
--
作者：
Gakuhari, Takashi;Nakagome, Shigeki;Oota, Hiroki
Takashi Gakuhari，Shigeki Nakagome等人报告了对来自当今日本古代绳文文化的2.5 kya个体的基因组分析。系统发育分析与其他欧亚序列的比较表明了亚洲早期的迁移模式，并提供了该地区人民之间遗传亲缘关系的见解。解剖学现代人类在4万多年前到达东亚。然而，关于向东欧亚大陆扩散的路线和波数的关键问题仍然没有答案。该地区边缘的古代基因组可能会阐明东欧亚大陆人口的更详细的情况。在这里，我们分析了一个2,500岁的个体（IK 002）的全基因组序列，该个体来自日本主岛，具有典型的绳文文化特征。系统发育分析支持多波移民，IK 002形成了东亚和东北亚基因组的基础谱系，可能代表了一些从东南亚向北迁移到东亚的最早的移民潮。此外，IK 002与台湾原住民有较强的遗传亲缘关系，可能支持其沿海岸线迁移。这项研究强调了古代基因组学的力量，为人类迁移到东欧亚大陆的复杂历史提供了新的见解。
Takashi Gakuhari, Shigeki Nakagome et al. report the genomic analysis on a 2.5 kya individual from the ancient Jomon culture in present-day Japan. Phylogenetic analysis with comparison to other Eurasian sequences suggests early migration patterns in Asia and provides insight into the genetic affinities between peoples of the region.Anatomically modern humans reached East Asia more than 40,000 years ago. However, key questions still remain unanswered with regard to the route(s) and the number of wave(s) in the dispersal into East Eurasia. Ancient genomes at the edge of the region may elucidate a more detailed picture of the peopling of East Eurasia. Here, we analyze the whole-genome sequence of a 2,500-year-old individual (IK002) from the main-island of Japan that is characterized with a typical Jomon culture. The phylogenetic analyses support multiple waves of migration, with IK002 forming a basal lineage to the East and Northeast Asian genomes examined, likely representing some of the earliest-wave migrants who went north from Southeast Asia to East Asia. Furthermore, IK002 shows strong genetic affinity with the indigenous Taiwan aborigines, which may support a coastal route of the Jomon-ancestry migration. This study highlights the power of ancient genomics to provide new insights into the complex history of human migration into East Eurasia.