GENETIC FACTOR INFLUENCING PULMONARY-HYPERTENSION IN CATTLE AT HIGH-ALTITUDE
GENETIC FACTOR INFLUENCING PULMONARY-HYPERTENSION IN CATTLE AT HIGH-ALTITUDE
复制标题
DOI：
10.1093/cvr/8.6.745
复制
发表时间：
1974-01-01
影响因子：
10.8
通讯作者：
GROVER, RF
中科院分区：
文献类型：
--
作者：
WEIR, EK;TUCKER, A;GROVER, RF
牛对高原肺动脉高压的易感性或抵抗性似乎是由遗传决定的，尽管其机制尚不清楚。易感动物的肺血管系统对前列腺素F2α的反应性未表现出更大的固有反应性。他们也没有一个更大的缺氧刺激在海拔高度由于换气不足。
AUTHORS' SYNOPSISSusceptibility or resistance to high altitude pulmonary hypertension in cattle appears to be determined genetically, although the mechanism is obscure. Susceptible animals did not exhibit greater intrinsic reactivity of the pulmonary vasculature in response to prostaglandin F2α. Neither did they have a greater hypoxic stimulus at altitude due to hypoventilation.