Comparisons and analysis of the hepatitis B infection status of transient population and registered residents in Shenzhen City
Comparisons and analysis of the hepatitis B infection status of transient population and registered residents in Shenzhen City
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发表时间：
2012
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通讯作者：
Zhu Qi-li
中科院分区：
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作者：
Zhu Qi-li
目的通过检测户籍居民和流动人口B肝炎血清标志物，了解其B肝炎感染状况及差异。方法采用多阶段整群随机抽样方法，于2010年7月~ 8月抽取户籍居民1 898人和流动人口1 873人，经问卷调查后采集血样，分别检测B肝炎病毒表面抗原（HBsAg）、B型肝炎病毒表面抗体（抗-HBs）和B型肝炎病毒核心抗体结果流动人口HBsAg阳性率为7.05%，略高于户籍居民（6.32%）;流动人口抗-HBs阳性率为67.16%，低于户籍居民（76.61%），流动人口和户籍居民各年龄组HBsAg阳性率差异无统计学意义（X2= 0.79，P =0.373），流动人口中文化程度低者HBsAg阳性率明显高于文化程度高者（X2=7.01，P=0.008），但不包括在内。深圳市出生的流动人口HBsAg阳性率低于其他省市出生的流动人口。深圳市流动人口的B型肝炎病毒感染比户籍居民严重得多，加强流动人口的常规免疫和查漏补种工作，对控制深圳市B型肝炎病毒的传播具有重要意义。
Objective To understand the hepatitis B infection status and differences of registered residents and transient population by detecting hepatitis B serum biomarkers in their blood.Methods With multi-stage cluster random sampling method,1 898 registered residents and 1 873 transient population were recruited in July and August,2010.Blood samples were collected after questionnaires.Hepatitis B virus surface antigen(HBsAg),hepatitis B virus surface antibody(anti-HBs) and hepatitis B virus core antibody(anti-HBc) were detected with enzyme-linked immunosorbent assay(ELISA).Results The positive rate of HBsAg in transient population was 7.05%,which was slightly higher than registered residents(6.32%);The positive rate of anti-HBs of transient population was 67.16%,which was lower than registered residents(76.61%).The positive rate of HBsAg in all age groups both in tansient population and registered residents had no significant difference(X2=0.79,P=0.373).Positive rate of HBsAg was much higher for people with low educated levels than that with high educated levels in transient population(X2=7.01,P=0.008).Transient population who were born in Shenzhen have lower HBsAg positive rate than those born in other provinces and cities.Conclusions The infection of hepatitis B virus of transient population is much more severe than registered residents in Shenzhen,thus it is of highly importance to strengthen normal immune and leakage searching reseed work in transient population for controlling the spread of hepatitis B virus in Shenzhen City.