Two Clinical Strains of Klebsiella pneumoniae Carrying Plasmid-Borne blaIMP-4, blaSHV-12, and armA Isolated at a Pediatric Center in Shanghai, China

Two Clinical Strains of Klebsiella pneumoniae Carrying Plasmid-Borne blaIMP-4, blaSHV-12, and armA Isolated at a Pediatric Center in Shanghai, China
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DOI:
10.1128/aac.01325-08
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发表时间:
2009-04-01
影响因子:
4.9
通讯作者:
Qin, Xuan
Qin, Xuan
中科院分区:
医学2区
文献类型:
--
作者:
Liu, Ying;Zhang, Bei;Qin, Xuan

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对2例肺炎克雷伯菌多重耐药菌株所致肺部感染进行了调查。β-内酰胺酶决定簇,如bla(IMP-4)和bla(SHV-12),以及编码16S rRNA甲基转移酶基因arma在这些携带质粒的微生物中被检测到。整合子携带的BLA(IMP-4)和ARMA含有与杭州发现的O139霍乱弧菌中国高度相关的插入序列。
Two cases of pulmonary infection due to strains of multidrug-resistant Klebsiella pneumoniae were investigated. Beta-lactamase determinants, such as bla(IMP-4) and bla(SHV-12), and the 16S rRNA methyltransferase-encoding gene armA were detected in these plasmid-bearing organisms. The integron-borne bla(IMP-4) and armA contained intervening sequences highly related to those of a Vibrio cholerae O139 plasmid found in Hangzhou, China.