A biosensing soft robot: Autonomous parsing of chemical signals through integrated organic and inorganic interfaces
A biosensing soft robot: Autonomous parsing of chemical signals through integrated organic and inorganic interfaces
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DOI：
10.1126/scirobotics.aax0765
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发表时间：
2019-06-26
期刊：
影响因子：
25
通讯作者：
Tan, Cheemeng
中科院分区：
文献类型：
--
作者：
Justus, Kyle B.;Hellebrekers, Tess;Tan, Cheemeng
合成生物学和软机器人的整合可以从根本上推进仿生机器的感官，诊断和治疗功能。然而，这种整合目前受到缺乏软物质架构的阻碍，该架构将合成细胞与电子器件和致动器连接起来，以在机器人操作期间进行受控刺激和响应。在这里，我们合成了一个柔软的抓手，它使用工程细菌来检测环境中的化学物质，一个柔性发光二极管（LED）电路用于将生物信号转换为电子信号，以及柔软的网状执行器用于将电子信号转换为抓手的运动。我们表明，混合生物LED致动器模块使夹具能够通过施加压力和释放注入化学品的水凝胶的内容物来检测化学信号。生物混合夹具使用化学传感和反馈，在拾取和放置操作期间做出可操作的决定。这项工作在软材料、合成生物学和集成界面机器人系统方面开辟了以前未识别的途径。
The integration of synthetic biology and soft robotics can fundamentally advance sensory, diagnostic, and therapeutic functionality of bioinspired machines. However, such integration is currently impeded by the lack of soft-matter architectures that interface synthetic cells with electronics and actuators for controlled stimulation and response during robotic operation. Here, we synthesized a soft gripper that uses engineered bacteria for detecting chemicals in the environment, a flexible light-emitting diode (LED) circuit for converting biological to electronic signals, and soft pneu-net actuators for converting the electronic signals to movement of the gripper. We show that the hybrid bio-LED-actuator module enabled the gripper to detect chemical signals by applying pressure and releasing the contents of a chemical-infused hydrogel. The biohybrid gripper used chemical sensing and feedback to make actionable decisions during a pick-and-place operation. This work opens previously unidentified avenues in soft materials, synthetic biology, and integrated interfacial robotic systems.