Gas dynamic virtual nozzle for generation of microscopic droplet streams
Gas dynamic virtual nozzle for generation of microscopic droplet streams
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DOI：
10.1088/0022-3727/41/19/195505
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发表时间：
2008-10-07
影响因子：
3.4
通讯作者：
Doak, R. B.
中科院分区：
文献类型：
--
作者：
DePonte, D. P.;Weierstall, U.;Doak, R. B.
如Ganan-Calvo（1998 Phys. Rev. Lett. 80285 -8），自由液体射流可以通过由同轴共流气体施加的气体动力在直径上被压缩，从而避免了对固体喷嘴的需要以形成微观液体射流，从而减轻了困扰常规小直径液滴源的堵塞问题。本文描述了一种新形式的液滴光束源的基础上，这一原则。该源是微型的、坚固的、可靠的、容易制造的，基本上不受堵塞的影响，并且非常适合于将微观液滴（包括水合生物样品）输送到真空中以使用真空仪器进行分析。通过用压电致动器触发装置来产生单分散、单列液滴流。
As shown by Ganan-Calvo (1998 Phys. Rev. Lett. 80 285-8), a free liquid jet can be compressed in diameter through gas dynamic forces exerted by a coaxially co-flowing gas, obviating the need for a solid nozzle to form a microscopic liquid jet and thereby alleviating the clogging problems that plague conventional droplet sources of small diameter. We describe in this paper a novel form of droplet beam source based on this principle. The source is miniature, robust, dependable, easily fabricated, essentially immune to clogging and eminently suitable for delivery of microscopic liquid droplets, including hydrated biological samples, into vacuum for analysis using vacuum instrumentation. Monodisperse, single-file droplet streams are generated by triggering the device with a piezoelectric actuator.