PHYTOCHEMICAL AND PHARMACOLOGICAL STUDIES OF DALBERGIA SISSOO GROWING IN EGYPT
PHYTOCHEMICAL AND PHARMACOLOGICAL STUDIES OF DALBERGIA SISSOO GROWING IN EGYPT
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DOI：
10.1076/phbi.37.1.54.6310
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发表时间：
1999
影响因子：
3.8
通讯作者：
T. Sarg;A. Ateya;A. Abdel-Ghani;W. Badr;G. Shams
中科院分区：
文献类型：
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作者：
T. Sarg;A. Ateya;A. Abdel-Ghani;W. Badr;G. Shams
从黄檀地上部分的绿枝中分离并鉴定了异黄酮类化合物伊索立酮、木犀草素-A、芒果异黄素、长春花素、李子素、染料木素、甜菜素和李子素-4-O-半乳糖苷、去甲胡萝卜素、S-香草素、S-谷甾醇和豆甾醇。采用硅胶柱层析和光谱分析。此外，还鉴定了13种脂肪酸。地上部分绿枝乙醇提取物对离体兔十二指肠运动有明显的抑制作用，具有明显的抗炎、解热、镇痛和雌激素样活性，且呈剂量依赖关系。该植物提取物对大鼠耐受性良好。
The isoflavones irisolidone, biochanin-A, muningin, tectorigenin, prunetin, genestein, sissotrin and prunetin-4- O -galactoside, the flavone nor-artocarpotin, and s-amyrin, s-sitosterol and stigmasterol were isolated and identified from the green branches of aerial parts of Dalbergia sissoo Roxb. using silica gel column chromatography and spectral analysis. Also, 13 fatty acids were identified. The alcohol extract of the green branches of aerial parts showed a dose-dependent inhibitory effect on the motility of isolated rabbit duodenum, pronounced bronchodilation, as well as significant anti-inflammatory, antipyretic, analgesic, and estrogen-like activities. The plant extract was well-tolerated by rats.